This is an important cancer-related study; so much so that Time Magazine featured it this week. Here’s an excerpt:
Mapping Cancer: Largest Set of Tumor Genomes Could Lead to Better Anticancer DrugsBy Alice Park – July 16, 2003
The latest map of all the genes involved in a set of tumor cells exposes which mutations drive cancer and how to possibly treat them.
The Human Genome Project provided the first glimpse of the power of genetic maps, and ever since, sequencing the DNA code of not just people but also tissues like tumors has become an invaluable tool in medicine. Laying out the biological code that instructs a fertilized egg to mature into the cells, tissues, organs and body systems that define a human being has led to important discoveries about how we get sick when those directions go awry.
And applying that same technique to cancer cells, experts are exposing some of the critical factors that drive cells to divide out of control to form tumors. In the latest advance, researchers at the National Cancer Institute have sequenced all of the genes in a cancer-cell database that was designed to test promising new drug compounds. With the most complete map of tumor aberrations now available, they can determine whether some of the failed drug candidates discarded over the years — there are thousands of them — may actually be useful in treating certain cancers.
What a great idea! Why recreate the wheel when a compound–or combination of compounds–already exists on the hard drive in a scientists office somewhere. There is so much more in Alice’s article. Read more by going to: