Chord blood transplants can be effective and are growing in popularity for use against a variety of blood cancers. I saw this study abstract in Saturday’s media packet. Glad journalist Raxanne Nelson followed-up on the story:
Double Cord Blood Transplant Better Than Single in Leukemia
December 5, 2010 (Orlando, Florida) — A double cord blood transplant (CBT) is not only feasible but also appears to be associated with better overall outcomes than a single CBT, according to new data presented here at the American Society of Hematology 52nd Annual Meeting. This was found to be particularly true when used early in the treatment of acute leukemias.
The use of double CBT extended the indication of allogenic hematopoietic transplantation in adult patients who were unable to obtain a single CBT unit with enough cell dose. In addition, explained lead author Vanderson Rocha, MD, scientific director of Eurocord Registry, Hôpital Saint-Louis, in Paris, France, the study confirmed the lower rate of relapse in patients who received a double CBT compared with a single CBT.
Previous research from the University of Minnesota has already shown that patients with acute leukemia who received a double CBT enjoy a lower incidence of relapse and a similar rate of leukemia-free survival.
The rate of leukemia-free survival was also improved in this study for patients transplanted with a double CBT in first complete remission, said Dr. Rocha.
“The result is that engraftment rate is the same between single and double CBT,” said Dr. Rocha during a press briefing held in advance of the presentation. “We have found and confirmed that you have higher incidence of graft-versus-host-disease [GVHD] in double CBT, but the mortality is not higher compared with single CBT.”
Feel good and keep smiling! Pat