Here is an enlightening report, written by Jimmy Downs for FoodConsumer.org, about how we all need to avoid eating foods which create a high insulin-like growth factor called IGF-I:

Meat, dairy products, sugar may up breast cancer risk – studies

In the pink month – the National Breast Cancer Awareness Month, we publish a report below to share with readers some studies that suggest eating meat, dairy products and sugar boosts breast cancer risk.

One study published in European Journal of Cancer suggests high levels of insulin-like growth factor -I or IGF-I boosts breast cancer risk.

The study led by J.P. Peyrat at Centre Oscar Lambret in France and colleagues measured this protein in the blood samples collected from patients with primary breast cancer and controls without the malignancy and found breast cancer patients had much higher levels of IGF-I.

IGF-I is a protein that is known to promote cell growth and inhibit apoptosis or programmed cell death, a combination that is seen commonly in malignant tumors. In vitro studies have already revealed that IGF-I is able to stimulate breast cancer cell growth, according to background information in the study report.

Among 44 breast cancer patients and 92 controls aged 35 or older, the average serum concentrations of IGF-I were found significantly higher in women with primary breast cancer than those without the disease, 26 ng/ml versus 20 ng/ml.

The researchers concluded that “We conclude that IGF-1 could be an important factor involved in the development of breast cancer and that treatment reducing IGF-1 levels could be beneficial for patients.”

Another study published in Breast Cancer Research and Treatment aslo found those who had the highest quartile of IGF-I were 92 percent more likely to be diagnosed with breast cancer than those with the lowest quartile of IGF-I.

Increased elevls of IGF-I were found in both premenopausal women and postmenopausal women who had breast cancer compared with that in controls. But the association was found only in Caucasian women, but not in Hispanic women.

Dana E. and colleagues at H. Lee Moffitt Cancer Center and Research Institute in Tampa, Florida conducted the study involving 184 cases of breast cancer and 522 controls.

In fact, quite some studies have suggested that IGF-I is a risk factor for breast cancer.

Helzlsouer KJ and colleagues from Endogenous Hormones and Breast Cancer Collaborative Group in the United Kingdom reviewed 17 prospective studies involving 4,790 cases of breast cancer and 9,428 matched controls in 12 countries and found those whose IGF-I levels were highest were 28 percent more likely to suffer breast cancer than those who had lowest levels.

Their findings were published in the June 2010 issue of the Lancet Oncology.

Other studies have shown high consumption of protein -rich foods likely meat, dairy products, milk, added sugar in processed foods and soft drinks, and some minerals are associated with elevated levels of IGF-I.

Dr. Colin T Campbell, a distinguished nutrition professor at Cornell University suggests in his book China Study that Americans eat too much protein, particularly animal protein.

Another recent study has found that older men who had higher levels of IGF-I were more likely to die from all cancers.

Breast cancer is diagnosed in more than 175,000 women and kills about 50,000 each year in the United States, according to the National Cancer Institute. The disease is expected in one in 7 women in their lifetime.

More reports will be published here in the National Breast Cancer Awareness Month to help readers understand that in many cases, breast cancer is preventable by simply following a modified lifestyle.

Wow!  World-wide studies conclude elevated I-GFI levels in a woman’s blood leads to a 28% higher breast cancer risk.  Now that’s significant.  We had all better re-read this article!

Feel good and keep smiling!  Pat & Pattie

Leave a Reply