Another great article from

Chemical in Broccoli Interacts With Cells to Reduce Prostate Cancer Risk

Broccoli Light has been cast on the interaction between broccoli consumption and reduced prostate cancer risk. Researchers have found that sulforaphane, a chemical found in broccoli, interacts with cells lacking a gene called PTEN developing.

Richard Mithen worked with a team of researchers to carry out a series of experiments in human prostate tissue and mouse models of prostate cancer to investigate the interactions between expression of the PTEN gene and the anti-cancer activity of sulforaphane. He said, “PTEN is a tumour suppressor gene, the deletion or inactivation of which can initiate prostate carcinogenesis, and enhance the probability of cancer progression. We’ve shown here that sulforaphane has different effects depending on whether the PTEN gene is present”.

The research team found that in cells which express PTEN, dietary intervention with SF has no effect on the development of cancer. In cells that don’t express the gene, however, sulforaphane causes them to become less competitive, providing an explanation of how consuming broccoli can reduce the risk of prostate cancer incidence and progression. According to Mithen, “This also suggests potential therapeutic applications of sulforaphane and related compounds”.

I eat broccoli everyday for a variety of reasons. Never hurts to add another reason–reduced risk of prostate cancer–to the list!

Feel good and keep smiling! Pat

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