Cancers, Research, Skin, Therapies
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I serve on the Patient Advisory Board of Millennium, makers of bortezomib (Velcade). I was excited to get this release today about possible cross-over application for use against stomach cancer:
PITTSBURGH, Jan. 12 (UPI) — A drug already approved for some cancers could be an effective treatment for a rare tumor found in the gastrointestinal tract, U.S. researchers said.
The drug Bortezomib, also known as Velcade, is used to treat multiple myeloma and some lymphomas, said pathologist Anette Duensing of the University of Pittsburgh School of Medicine.
In tests, Bortezomib showed promise against gastrointestinal stromal tumor cells. The stromal tumor cells usually are treated with imatinib, or Gleevec, which is effective initially but rarely kills the cells completely, Duensing and her team wrote in a recent issue of Cancer Research.
Bortezomib suppressed the cancer cells’ production of an enzyme called KIT and was active against imatinib-resistant cells.
“This is intriguing because resistance to imatinib seems to permit a small pool of quiescent cancer cells to survive,” Duensing said. “But Bortezomib eradicates KIT production, so it might be able to rid the body of the remaining tumor cells.”
Looks promising! Feel good and keep smiling! Pat
Stomach cancer is also called as gastric cancer. It develops in the tissues that line the stomach. Some of its symptoms are discomfort in stomach, feeling fullness even after eating small portion meal, weight loss, feeling like vomiting etc. The reason for stomach cancer is still unknown by many doctors, so if one observes the symptoms of it, should immediately consult doctor. For more information on it, refer Stomach cancer symptoms